New research shows that sustained activation of the innate immune receptor TLR4 in podocytes triggers a reversible leak in ...

Unlike other human stem cells, Induced pluripotent stem cells (iPS cells) can be produced directly from adult cells. Now, researchers have shown that human kidney podocytes produced from iPS cells via ...

BUFFALO, NY-August 8, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, “Inhibiting ...

New research shows that arachidonic acid released during infection worsens podocyte kidney injury by disrupting PKM2-linked ...

Clinically approved drugs induced ChAT expression and acetylcholine production in podocytes in vivo, suggesting the pathway could be pharmacologically targeted.

A new research paper titled "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span" has been published in Aging. The decrease in the podocytes' lifespan and health span ...

A: This is a structure of glomerulus. B: Magnified picture of podocytes showing many protrusions. C: Schematic diagram of the filtration membrane between the protrusions of podocytes. Nephrin, the ...

A unique tool for the study of human glomerular disease. It is known and used worldwide by leading research groups and many of the world’s largest pharmaceutical companies. This conditionally ...

The kidneys are vital organs that sustain life by filtering the blood and producing urine. This filtration process takes place in specialized structures called glomeruli, where podocytes play a ...

A newly-established protocol offers hope for kidney disease modeling, drug discovery, and potential cell therapies. Previous work from the Wyss Institute at Harvard University established a protocol ...